Radiofrequency ablation of hepatocellular carcinoma: Value of virtual CT sonography with magnetic navigation
Radiofrequency ablation of hepatocellular carcinoma: Value of virtual CT sonography with magnetic navigation
复制标题
DOI：
10.2214/ajr.07.3092
复制
发表时间：
2008-06-01
影响因子：
5
通讯作者：
Shiozaki, Hitoshi
中科院分区：
文献类型：
--
作者：
Minami, Yasunori;Chung, Hobyung;Shiozaki, Hitoshi
目标。具有磁性导航的虚拟CT超声成像可实时生成与换能器在磁场中的角度相对应的CT体积数据的横截面图像。本研究的目的是评价虚拟CT超声对B超显示不清的多血管肝细胞癌进行射频消融的有效性和可行性。材料和方法。参加研究的101名患者被分成两组。对51例65个肝细胞癌患者进行了前瞻性虚拟CT超声检查，以指导射频消融。结果：在虚拟CT超声组中，一次消融成功率为92%(47/51)，两次消融成功率为8%(4/51)。在B超组中，72%(36/50)的患者在一次治疗中取得了技术成功，24%(12/50)的患者在两次治疗中取得了技术上的成功，4%(2/50)的患者在三次治疗中取得了成功。处理分析显示，虚拟CT超声组在单次治疗后的技术成功率显著更高(p=0.017)。虚拟CT超声组治疗次数明显减少(p=0.021)(平均1.1+/-0.1vs1.3+/-0.3次)。结论：虚拟CT超声辅助射频消融术是治疗B超诊断不清的肝细胞癌的有效方法。
OBJECTIVE. Virtual CT sonography with magnetic navigation yields cross-sectional images of CT volume data that correspond to the angle of the transducer in the magnetic field in real time. The purpose of this study was to evaluate the efficiency and feasibility of virtual CT sonography for radiofrequency ablation of hypervascular hepatocellular carcinoma poorly defined on B-mode sonography.MATERIALS AND METHODS. One hundred one patients enrolled in the study were separated into two groups. Fifty-one patients with 65 hepatocellular carcinomas underwent prospective virtual CT sonography as guidance for radiofrequency ablation. Fifty patients with 63 hepatocellular carcinomas managed with B-mode sonographic guidance were retrospectively selected under the same conditions as the virtual CT sonography group to act as a historical control group.RESULTS. In the virtual CT sonography group, technically successful ablation was achieved in a single session in 92% (47/51) of the patients and in two sessions in 8% (4/51). In the B-mode sonography group, technical success was achieved in a single session in 72% (36/50) of the patients, in two sessions in 24% (12/50), and in three sessions in 4% (2/50). Treatment analysis showed that the technical success rate after a single treatment session was significantly (p = 0.017) higher for the virtual CT sonography group. The number of treatment sessions was significantly (p = 0.021) lower for the virtual CT sonography group (mean, 1.1 +/- 0.1 vs 1.3 +/- 0.3 sessions).CONCLUSION. Virtual CT sonographically assisted radiofrequency ablation is an efficient treatment of patients with hepatocellular carcinoma that is poorly defined on B-mode sonography.