Brief report: preoperative frailty in older surgical patients is associated with early postoperative delirium.
Brief report: preoperative frailty in older surgical patients is associated with early postoperative delirium.
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DOI：
10.1213/ane.0b013e31820c7c06
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发表时间：
2011-05
影响因子：
5.7
通讯作者：
Sands LP
中科院分区：
文献类型：
--
作者：
Leung JM;Tsai TL;Sands LP
在老年非心脏手术患者中，我们调查了术前虚弱是否提供了除传统老年危险因素外术后谵妄发生的信息。三分之一的患者虚弱评分≥ 3，在其他研究中被认为是“虚弱”。25%的患者出现术后谵妄，这是使用混乱评估方法测量的。多因素Logistic回归分析显示，年龄、日常生活活动依赖性、独立日常生活活动依赖性和认知功能对术后谵妄的预测作用不显著。只有术前抑郁症状（OR=1.42; 95% CI=1.06-1.91; p=0.018）和虚弱评分（OR=1.84; 95% CI=1.07-3.1; p=0.028）与术后谵妄的发生独立相关。
Among older noncardiac surgical patients, we investigated whether preoperative frailty provides information about the development of postoperative delirium that is in addition to traditional geriatric risk factors. One-third of patients had a frailty score ≥ 3, which is considered ‘frail’ in others’ research. Twenty-five percent of patients developed postoperative delirium, which was measured using the Confusion Assessment Method. Multivariable logistic regression showed that age, activities of daily living dependence, independent activities of daily living dependence and cognitive functioning did not contribute significantly to the prediction of postoperative delirium. Only preoperative symptoms of depression (OR=1.42; 95% CI=1.06–1.91; p=0.018) and the frailty score (OR=1.84; 95% CI=1.07–3.1; p=0.028) were independently associated with the development of postoperative delirium.