Monte Carlo study of the beam shaping assembly optimization for providing high epithermal neutron flux for BNCT based on D-T neutron generator
Monte Carlo study of the beam shaping assembly optimization for providing high epithermal neutron flux for BNCT based on D-T neutron generator
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基于D-T中子发生器为BNCT提供高超热中子通量的束流成形组件优化的蒙特卡罗研究
DOI：
10.1007/s10967-016-5001-4
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发表时间：
2016
影响因子：
1.6
通讯作者：
Chen Da
中科院分区：
文献类型：
--
作者：
Hang Shuang;Tang Xiaobin;Shu Diyun;Liu Yuanhao;Geng Changran;Gong Chunhui;Yu Haiyan;Chen Da
本文基于D-T中子发生器，利用蒙特卡罗N粒子输运程序，设计了一种高通量超热中子束流整形装置。根据硼中子俘获治疗的要求，采用D2 O-54 Fe和AlF 3 - 60 Ni中间层慢化剂、高效倍增器、滤光片和反射层等材料，在保证超热中子束流高通量的同时，改善了束流质量。此外，在Snyder头部体模中评估了来自我们建议设施的射束的剂量性能。模拟结果表明，该中子束可用于深部脑肿瘤的治疗。
In this study, a beam shaping assembly with high epithermal neutron flux output was designed based on a D–T neutron generator using Monte Carlo N-particle Transport Code. D2O-54Fe and AlF3-60Ni interlayer moderator, efficient multiplier, filters, and reflector were used to improve the neutron beam quality according to the requirements of boron neutron capture therapy while maintaining high flux of epithermal neutron beam. In addition, the dose performance of the beam from our proposed facility was assessed in the Snyder head phantom. The simulation results proved that the proposed neutron beam was applicable to the treatment of deep-seated brain tumor.