Diosmectite-zinc oxide composite improves intestinal barrier function, modulates expression of pro-inflammatory cytokines and tight junction protein in early weaned pigs
Diosmectite-zinc oxide composite improves intestinal barrier function, modulates expression of pro-inflammatory cytokines and tight junction protein in early weaned pigs
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硅皂石-氧化锌复合物改善早期断奶猪的肠道屏障功能，调节促炎细胞因子和紧密连接蛋白的表达
DOI：
10.1017/s0007114512005508
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发表时间：
2013-08-28
影响因子：
3.6
通讯作者：
Zhu, Kang
中科院分区：
文献类型：
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作者：
Hu, Caihong;Song, Juan;Zhu, Kang
本研究旨在评价以500 mg Zn/kg的蒙脱石-ZnO复合物（DS-ZnO）替代高浓度ZnO（2250 mg Zn/kg）饲喂早期断奶仔猪是否能缓解断奶相关的肠道疾病。将21 +/-1日龄断奶的猪分为以下四个处理组：（1）对照组;（2）DS-ZnO，500 mg Zn/kg日粮;（3）ZnO，2250 mg Zn/kg日粮;和（4）2.0 g DS/kg和500 mg Zn/kg ZnO的混合物（DS-ZnO处理组中DS和ZnO的量相等）。结果表明，在断奶后7天和14天，添加500 mg Zn/kg的DS-ZnO组与对照组相比，增重效果显著（P
The study evaluated whether feeding diosmectite-ZnO composite (DS-ZnO) at 500 mg Zn/kg to early weaned pigs would alleviate the weaning-related intestinal disorders as a substitute for high concentration of ZnO (2250 mg Zn/kg). The pigs weaned at an age of 21 +/- 1 d were allotted to four treatments groups as follows: (1) control; (2) DS-ZnO, 500 mg Zn/kg diet; (3) ZnO, 2250 mg Zn/kg diet; and (4) mixture of 2.0 g DS/kg and 500 mg Zn/kg from ZnO (equal amount of DS and ZnO in the DS-ZnO treatment group). The results showed that, compared with the control on days 7 and 14 post-weaning, addition of DS-ZnO at 500 mg Zn/kg improved (P