Frequency Dependent Attenuation in Normal and Diseased Livers
Frequency Dependent Attenuation in Normal and Diseased Livers
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正常和患病肝脏中的频率依赖性衰减
DOI：
10.1109/ultsym.1986.198843
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
R. Waag
中科院分区：
文献类型：
--
作者：
K. Parker;M. Asztély;R. Lerner;E. Schenk;R. Waag
肝脏衰减系数的幅度和频率依赖性是通过对改进的 B 扫描成像仪器的超声回波的信号处理得出的。对 59 名个体的肝脏扫描数据进行了分析，其中 21 例被认为正常，其余则涉及弥漫性肝病，如酒精性肝病、化疗毒性、肝转移等。结果表明，人类肝脏的正常衰减值为 0.0542 0.009 np/cm-MHz（或 0.47 db/cm-MHz），频率依赖性为 fn，其中 n=1.05 i 0.25。与哺乳动物肝脏的体外研究一致。进一步的分析显示，衰减系数与 CT 或常规超声检查结果或肝活检分级的纤维化程度之间没有显着关系。然而，高衰减与肝功能测试异常之间存在显着相关性。高衰减还与摄入酒精、化疗药物和类固醇有关，所有这些都可能作为影响肝脏脂肪含量的常见途径。
The magnitude a nd frequency dependence of liver attenuation coefficients have been derived from signal processing o f ultrasonic echoes from a modified B-scan imaging instrument. Data were analyzed from liver scans of 59 individuals, of which 21 cases were presumed normal, and the remainder involved with diffuse liver disease such as alcoholic liver disease, chemotherapy toxicity, liver metastases, and others. The results show that normal attenuation values for human liver are 0.0542 0.009 np/cm-MHz (or 0.47 db/cm-MHz) with a frequency dependence of fn where n=1.05 i 0.25. in agreement with in-vitro studies of mammalian livers. Further analyses showed no significant r elationship between attenuation coeffcients and results of CT or conventional ultrasonic examination, or the degree of fibrosis as graded from liver biopsies. However, a significant correlation was found between high attenuation and a bnormal liver function tests. High attenuation is also associated with ingestion of alcohol, chemotherapeutic agents, and steroids, all of which may affect liver fat content as a common pathway.
影响因子：
2.4
作者：
PARKER, KJ
通讯作者：
PARKER, KJ