Semiquantitative imaging measurement of baseline and vasomodulated normal prostatic blood flow using sildenafil.
Semiquantitative imaging measurement of baseline and vasomodulated normal prostatic blood flow using sildenafil.
复制标题
使用西地那非对基线和血管调节正常前列腺血流进行半定量成像测量。
DOI:
10.1038/sj.ijir.3901486
复制
发表时间:
2007
影响因子:
2.6
通讯作者:
Seftel,A
中科院分区:
文献类型:
--
作者:
Haaga,JR;Exner,A;Fei,B;Seftel,A
The physiologic variability of blood flow to the prostate has not been studied until this time. We report the vasoactive effects of sildenafil and phenylephrine on blood flow of the normal prostate. Sildenafil increases prostate blood flow by approximately 75% and phenylephrine reduces the flow incrementally. Administration of these drugs with dynamic contrast-enhanced magnetic resonance imaging may improve the diagnosis of cancerous tissue because according to the literature, tumor angiogenic vessels lack the vasoactive physiologic response of the normal tissue.