Q fever with clinical features resembling systemic lupus erythematosus
Q fever with clinical features resembling systemic lupus erythematosus
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DOI：
10.2169/internalmedicine.45.1382
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发表时间：
2006-01-01
影响因子：
1.2
通讯作者：
Sasaki, Takeshi
中科院分区：
文献类型：
--
作者：
Ohguchi, Hiroto;Hirabayashi, Yasuhiko;Sasaki, Takeshi
一名23岁女性，长期发热，皮疹，心包炎与高滴度的抗核，抗Sm，抗RNP抗体被怀疑有系统性红斑狼疮（SLE）。然而，我们也考虑了感染性疾病，特别是Q热，因为C反应蛋白水平升高，并且患者报告在发病前两周左右与动物园动物接触。服用米诺环素后，病情迅速缓解;无需使用类固醇，症状即可消退。此后，未观察到疾病复发。贝氏柯克斯体抗体滴度高，诊断为急性Q热而非SLE。
A 23-year-old woman with prolonged fever, rash, and pericarditis associated with high titers of antinuclear, anti-Sm, and anti-RNP antibodies was suspected of having systemic lupus erythematosus (SLE). However, we also considered infectious diseases, particularly Q fever, as the C-reactive protein level was elevated and the patient reported contact with zoo animals around two weeks before the onset. The condition responded rapidly to administration of minocycline; symptoms resolved without using steroids. Thereafter, no recurrence of the illness was observed. Titer of Coxiella burnetii antibody was high and the illness was accordingly diagnosed as acute Q fever rather than SLE.