Di‐n‐butyltin aminoarylcarboxylates: structure, properties and in vitro antitumor activity
Di‐n‐butyltin aminoarylcarboxylates: structure, properties and in vitro antitumor activity
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DOI：
10.1002/aoc.347
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发表时间：
2002-10
影响因子：
3.9
通讯作者：
F. Pruchnik;Małgorzata Bańbuła;Z. Ciunik;H. Chojnacki;M. Latocha;B. Skop;T. Wilczok
中科院分区：
文献类型：
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作者：
F. Pruchnik;Małgorzata Bańbuła;Z. Ciunik;H. Chojnacki;M. Latocha;B. Skop;T. Wilczok
The properties and structures of the tetranuclear dibutyltin complexes [Sn 4 (μ 3 -O) 2 (C 4 H 9 -n) 8 {OOCC 6 H 3 (NH 2 ) 2 -3,4) 4 ] (1), [Sn 4 (μ 3 -O) 2 (C 4 H 9 -n) 8 {OOCC 6 H 3 (NH 2 ) 2 -3,5} 4 ] (2), [Sn 4 (μ 3 -O) 2 (C 4 H 9 -n) 8 {OOC-2-C 6 H 4 N=NC 6 H 4 N(CH 3 ) 2 -4} 4 ] (3) are described. Complex 3 adopts a structure with a tetranuclear Sn 4 (μ 3 -O) 2 core. All tin atoms are five-coordinate and form bonds with three oxygen atoms and two butyl ligands. Two carboxylates are bridging and two are terminal ligands. IR and NMR spectra indicate that the same structure is adopted by complexes 1 and 2. The molecular and electronic structures of complex 1 of C i symmetry have been studied using the semi-empirical PM3 formalism. The calculated structure and bond distances agree with X-ray data. All complexes are effective antitumor agents.
