Clinical Digital Breast Tomosynthesis System: Dosimetric Characterization
Clinical Digital Breast Tomosynthesis System: Dosimetric Characterization
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DOI：
10.1148/radiol.11111789
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发表时间：
2012-04-01
期刊：
影响因子：
19.7
通讯作者：
Sechopoulos, Ioannis
中科院分区：
文献类型：
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作者：
Feng, Steve Si Jia;Sechopoulos, Ioannis
目的：为了全面表征临床数字乳腺断层合成摄影（DBT）系统用于采集乳腺X线摄影和断层合成摄影images.Materials和Methods的剂量学特性：可压缩的水油混合物phantomenum创建和成像通过使用自动曝光控制（AEC）的Selenia尺寸系统（Hologic，贝德福德，马萨诸塞州）在DBT和全视野数字乳腺X线摄影（FFDM）模式。使用剂量计对X射线管输出进行经验测量，以测量管电流-曝光时间乘积设置范围内的空气比释动能，并开发自动选择的X射线光谱模型。系统的Monte Carlo模拟被开发并与AEC选择的设置和光谱模型结合使用，以计算和比较不同大小和腺体组成的乳房的两种成像模式产生的平均腺体剂量（MGD）。结果：在FFDM模式下采集单个头尾位视图导致MGD范围为0.309至5.26 mGy，在DBT模式下为0.657至3.52 mGy。对于压缩厚度为5.0 cm且腺体分数为50%的乳房，DBT采集的MGD仅比FFDM采集高8%（分别为1.30和1.20 mGy）。对于压缩厚度为6.0 cm且腺体分数为14.3%的乳房，DBT采集的MGD比FFDM采集高83%（分别为2.12和1.16 mGy）。对于使用Selenia Dimensions系统的二维-三维融合成像，5 cm厚50%腺体乳腺的MGD为2.50 mGy，这低于乳房X线摄影质量标准法案对双视图筛查乳房X线摄影研究的限制。(C)RSNA，2012年
Purpose: To comprehensively characterize the dosimetric properties of a clinical digital breast tomosynthesis (DBT) system for the acquisition of mammographic and tomosynthesis images.Materials and Methods: Compressible water-oil mixture phantoms were created and imaged by using the automatic exposure control (AEC) of the Selenia Dimensions system (Hologic, Bedford, Mass) in both DBT and full-field digital mammography (FFDM) mode. Empirical measurements of the x-ray tube output were performed with a dosimeter to measure the air kerma for the range of tube current-exposure time product settings and to develop models of the automatically selected x-ray spectra. A Monte Carlo simulation of the system was developed and used in conjunction with the AEC-chosen settings and spectra models to compute and compare the mean glandular dose (MGD) resulting from both imaging modalities for breasts of varying sizes and glandular compositions.Results: Acquisition of a single craniocaudal view resulted in an MGD ranging from 0.309 to 5.26 mGy in FFDM mode and from 0.657 to 3.52 mGy in DBT mode. For a breast with a compressed thickness of 5.0 cm and a 50% glandular fraction, a DBT acquisition resulted in an only 8% higher MGD than an FFDM acquisition (1.30 and 1.20 mGy, respectively). For a breast with a compressed thickness of 6.0 cm and a 14.3% glandular fraction, a DBT acquisition resulted in an 83% higher MGD than an FFDM acquisition (2.12 and 1.16 mGy, respectively).Conclusion: For two-dimensional-three-dimensional fusion imaging with the Selenia Dimensions system, the MGD for a 5-cm-thick 50% glandular breast is 2.50 mGy, which is less than the Mammography Quality Standards Act limit for a two-view screening mammography study. (C) RSNA, 2012