The oral microbial community of gingivitis and lumpy jaw in captive macropods
The oral microbial community of gingivitis and lumpy jaw in captive macropods
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DOI：
10.1016/j.rvsc.2013.08.010
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发表时间：
2013-12-01
影响因子：
2.4
通讯作者：
Ball, Andrew S.
中科院分区：
文献类型：
--
作者：
Antiabong, John F.;Boardman, Wayne;Ball, Andrew S.
牙龈炎和龈下炎是多种微生物病因的疾病。虽然坏死梭杆菌已与这些疾病的macropods，很少有人知道其他生物与这些疾病在这种动物物种。PCR-DGGE分析揭示了与大型节肢动物牙龈炎和下颌骨肥大相关的潜在病原体。PCR-DGGE图谱比较健康和疾病组之间的口腔细菌群落结构的变化与牙龈炎和光泽颌的相似系数分别为48%和35%。此外，牙龈炎与细菌多样性的增加（香农指数= 2.87; PL曲线= 45%），而lucidal颌骨导致细菌多样性的下降（香农指数= 2.47; PL曲线= 74%）。这项研究表明，牙龈炎和lucidal颌骨疾病的建立遵循生态菌斑假说。这构成了在流行病学规模上扩大调查的基础，并表明需要适当选择抗菌剂，有效管理和控制多种微生物疾病。(C)2013爱思唯尔有限公司保留所有权利。
Gingivitis and lumpy jaw are diseases of polymicrobial aetiology. Although Fusobacterium necrophorum has been associated with these diseases in macropods, little is known about other organisms associated with these diseases in this animal species. PCR-DGGE analysis revealed the potential pathogens associated with gingivitis and lumpy jaw in macropods. PCR-DGGE profile comparison between the healthy and disease groups indicated a shift in the oral bacterial community structures with similarity coefficients of 48% and 35% for gingivitis and lumpy jaw respectively. Moreover, gingivitis was associated with increase in bacterial diversity (Shannon index = 2.87; PL curve = 45%) while lumpy jaw resulted in a decline in bacterial diversity (Shannon index = 2.47; PL curve = 74%). This study suggest that the establishment of gingivitis and lumpy jaw diseases follows the ecological plaque hypothesis. This forms the basis for an expanded investigation in an epidemiological scale and suggests the need for the appropriate choice of antimicrobial agent(s) and for the effective management and control of polymicrobial diseases. (C) 2013 Elsevier Ltd. All rights reserved.