Genetic variants of carbonic anhydrase in the Asian-Pacific area.
Genetic variants of carbonic anhydrase in the Asian-Pacific area.
复制标题
亚太地区碳酸酐酶的遗传变异。
DOI：
10.1080/03014467800003241
复制
发表时间：
1978
影响因子：
1.7
通讯作者：
N. M. Blake
中科院分区：
文献类型：
--
作者：
N. M. Blake
对亚太地区红细胞碳酸酐酶表型的广泛调查结果与仅存在于澳大利亚土著人的三种新多态性的发生数据一起提出。其中两种语言系统在澳大利亚大陆广泛使用，而剩下的一种则仅限于阿纳姆地的一个单一语言群体的成员。本文还报道了CA1 -1 -关岛的进一步例子，以及CA1 -1 -新加坡的电泳迁移率与CA1 -1 -1关岛的电泳迁移率难以区分。表格中包括亚太地区以外其他人群的数据，为了完整起见，还包括已经公布的CA1和CA2变异的信息。为了简化碳酸酐酶变体的命名，提出了一种新的命名系统，使用数字而不是字母来区分变体同工酶。还描述了电泳缓冲系统的改进，以增强CA1等位基因的几个产物之间存在的极小的迁移率差异。
The results of extensive surveys of red cell carbonic anhydrase phenotypes in the Asian-Pacific region are presented together with data on the occurrence of three new polymorphisms present only in Australian Aboriginals. Two of these systems are widespread right across the Australian continent, while the remaining one is restricted to members of a single linguistic group in Arnhem Land. Further examples of CA1 3-1 Guam are reported, and also CA1 3-1 Singapore which has an electrophoretic mobility indistinguishable from that of CA1 3-1 Guam. Included in the tabulations are data on other populations outside the Asian-Pacific area and, for completeness, information already published on variants of both CA1 and CA2. In an effort to simplify the nomenclature of carbonic anhydrase variants, a new system is suggested, using numerals rather than letters to distinguish the variant isozymes. Modifications of the electrophoresis buffer system which enhances the very small mobility differences existing between several of the products of the CA1 alleles are also described.