Fatal hemorrhagic pneumonia caused by human metapneumovirus in an immunocompetent child
Fatal hemorrhagic pneumonia caused by human metapneumovirus in an immunocompetent child
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免疫功能正常儿童由人类偏肺病毒引起的致命性出血性肺炎
DOI：
10.1111/j.1442-200x.2008.02673.x
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发表时间：
2008
影响因子：
1.4
通讯作者：
M. Ferrés
中科院分区：
文献类型：
--
作者：
A. Donoso;J. León;J. Camacho;P. Cruces;M. Ferrés
© 2008日本儿科学会人类偏肺病毒（hMPV）最近于2001年在荷兰被发现。这种病原体会引起儿童和成人的急性呼吸道感染。1临床表现范围从无症状感染者到重症肺炎、急性呼吸衰竭不等。1 - 3当这种病原体与呼吸道合胞病毒（RSV）共存于毛细支气管炎时，症状更严重。4威廉姆斯等人在超过25年的调查中发现，12%的儿童下呼吸道感染是由hMPV引起的。2
© 2008 Japan Pediatric Society Human metapneumovirus (hMPV) was recently discovered in 2001 in Holland. This agent causes acute respiratory tract infections in children and adults. 1 The range of clinical manifestations varies from asymptomatic infection to severe pneumonia and acute respiratory failure. 1 – 3 When this agent coexists with the respiratory syncytial virus (RSV) in bronchiolitis, symptoms are more severe. 4 Williams et al. found, in more than 25 years of investigation, that 12% of lower respiratory tract infections in children was caused by hMPV. 2