Arterial Mesenteric Thrombosis as a Complication of SARS-CoV-2 Infection.

Arterial Mesenteric Thrombosis as a Complication of SARS-CoV-2 Infection.
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DOI:
10.12890/2020_001690
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发表时间:
2020-01-01
影响因子:
--
通讯作者:
Cuzzoli, Antonio
Cuzzoli, Antonio
中科院分区:
其他
文献类型:
--
作者:
A Beccara, Lia;Pacioni, Carlotta;Cuzzoli, Antonio

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一名 52 岁 SARS-CoV-2 患者被诊断患有间质性肺炎,并接受达芦那韦/利托那韦、羟氯喹、阿奇霉素和低分子肝素 (LMWH) 治疗。 LMWH 停止后,他出现肠系膜上动脉血栓形成。腹部CT扫描显示肠系膜上动脉传出血管血栓形成并伴有肠扩张。 COVID-19 可能导致静脉和动脉血栓栓塞。应考虑对住院的 COVID-19 患者进行抗凝预防,并对每位受 SARS-CoV-2 感染的有症状患者进行潜在血栓栓塞调查。学习要点:必须对每位有症状的 SARS-CoV-2 感染患者进行潜在血栓栓塞调查。应强烈考虑使用抗血栓药物进行预防和治疗,以减轻 SARS-CoV-2 感染患者的血栓和出血事件。
A 52-year-old patient with SARS-CoV-2 was diagnosed with interstitial pneumonia and treated with darunavir/ritonavir, hydroxychloroquine, azithromycin and low molecular weight heparin (LMWH). After LMWH cessation, he developed superior mesenteric arterial thrombosis. An abdominal CT scan showed arterial thrombosis of vessels efferent of the superior mesenteric artery with bowel distension. COVID-19 may predispose to venous and arterial thromboembolism. Anticoagulation prophylaxis should be considered in hospitalized patients with COVID-19, and potential thromboembolism investigated in each symptomatic patient affected by SARS-CoV-2.LEARNING POINTS: Potential thromboembolism must be investigated in each symptomatic patient with SARS-CoV-2 infection.The preventive and therapeutic use of antithrombotic agents should be strongly considered in order to mitigate thrombotic and haemorrhagic events in patients with SARS-CoV-2 infection.