Multiple left-sided cardiac lesions in one of Noonan's original patients.
Multiple left-sided cardiac lesions in one of Noonan's original patients.
复制标题
努南最初的一位患者出现多处左侧心脏病变。
DOI：
10.1017/s1047951100005679
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发表时间：
1999
影响因子：
1
通讯作者：
Embrey,RP
中科院分区：
文献类型：
--
作者：
Danetz,JS;Donofrio,MT;Embrey,RP
我们描述了一个复杂的情况下，梗阻的左心室流出道博士努南的原始病人之一。术中发现在瓣、瓣下和瓣上位置有病理学改变。努南综合征患者传统上被描述为具有右侧心脏病理。文献综述显示，这些患者中有相当一部分发生左侧病变。因此，我们建议对所有努南综合征患者进行常规心脏超声检查，注意左侧病变以及常见的肺动脉瓣病变。
We describe a complex case of obstruction of the left ventricular outflow tract in one of Dr. Noonan's original patients. Intraoperative findings revealed pathology at the valvar, subvalvar and supravalvar positions. Patients with Noonan syndrome are traditionally described as having right-sided cardiac pathology. Review of the literature revealed left-sided lesions to occur in a substantial number of these patients. We therefore suggest the routine employment of cardiac ultrasonography in all patients with Noonan syndrome with attention directed toward left-sided pathology, as well as the frequent pulmonary valvar pathology.