Preparation of a Stable Trifluoroborate Salt for the Synthesis of 1-Aryl-2,2-difluoro-enolethers and/or 2,2-Difluoro-1-aryl-ketones via Palladium-Mediated Cross-Coupling

Preparation of a Stable Trifluoroborate Salt for the Synthesis of 1-Aryl-2,2-difluoro-enolethers and/or 2,2-Difluoro-1-aryl-ketones via Palladium-Mediated Cross-Coupling
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DOI:
10.1021/jo901789b
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发表时间:
2009-11-20
影响因子:
3.6
通讯作者:
Dinsmore, Christopher J.
Dinsmore, Christopher J.
中科院分区:
化学2区
文献类型:
--
作者:
Katz, Jason D.;Lapointe, Blair T.;Dinsmore, Christopher J.

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A bench-stable potassium trifluoroborate enol ether reagent has been prepared. This reagent is suitable for the incorporation of 2,2-difluoroenolethers into aryl and heteroaryl systems via palladium-mediated cross-coupling with suitable halide coupling partners.