Diagnosis and classification of adult Still's disease

Diagnosis and classification of adult Still's disease
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DOI:
10.1016/j.jaut.2014.01.011
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发表时间:
2014-02-01
影响因子:
12.8
通讯作者:
Amital, Howard
Amital, Howard
中科院分区:
医学1区
文献类型:
--
作者:
Mahroum, Naim;Mahagna, Hussein;Amital, Howard

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成人发病的斯蒂尔氏病的基础是每日发烧、关节炎和皮疹的三联征。这种综合征仍然是个谜,而且通常是一种排斥疾病。既有肌肉骨骼特征,也有全身特征。更重要的是,患者可能出现反应性噬血细胞综合征。在这篇综述中,我们试图把这种综合征的观点,包括数据的地理流行病学,临床和实验室的特点。(C) 2014 Elsevier Ltd.版权所有。
The cornerstone of adult onset Still's disease is the triad of daily fever, arthritis and rash. This syndrome remains enigmatic and most often a disease of exclusion. There are both musculoskeletal as well as systemic features. More importantly, reactive hemophagocytic syndrome may occur in patients. In this review we attempt to place this syndrome in perspective, including data on geoepidemiology, clinical and laboratory features. (C) 2014 Elsevier Ltd. All rights reserved.