How lymphocytes kill.
How lymphocytes kill.
复制标题
淋巴细胞如何杀死。
DOI：
10.1146/annurev.me.41.020190.000401
复制
发表时间：
1990
影响因子：
10.5
通讯作者：
Young,JD
中科院分区：
文献类型：
--
作者：
Young,LH;Liu,CC;Joag,S;Rafii,S;Young,JD
细胞毒性T淋巴细胞和自然杀伤细胞是靶细胞的强效杀伤细胞。这些淋巴细胞具有含有细胞毒性肽和其他因子的大细胞质颗粒。这些分子中有几个已经被分离出来，并阐明了它们的功能。这些分子可能直接参与杀死病毒感染和转化的细胞以及细胞介导的自身免疫性疾病的发展。
Cytotoxic T lymphocytes and natural killer cells are potent killers of target cells. These lymphocytes have large cytoplasmic granules containing cytotoxic peptides and other factors. Several of these molecules have been isolated and their functions elucidated. These molecules may be directly involved in the killing of virus-infected and transformed cells as well as in the development of cell-mediated autoimmune disorders.