The impact of metabolic stress on hormonal responses and muscular adaptations
The impact of metabolic stress on hormonal responses and muscular adaptations
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DOI：
10.1249/01.mss.0000170470.98084.39
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发表时间：
2005-06-01
期刊：
影响因子：
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通讯作者：
Takamatsu, K
中科院分区：
文献类型：
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作者：
Goto, K;Ishii, N;Takamatsu, K
目的：本研究的目的是研究运动引起的代谢应激对激素反应和慢性肌肉适应的影响。研究方法：我们比较了“NR方案”（无休息方案）和“WR方案”（在一组中有休息期的方案）的急性和长期效果。将26例男性受试者分配至NR（N = 9）、WR（N = 9）或对照（CON，N = 8）组。NR方案包括3-5组，每组10次重复，最大重复次数为10次（RM），间隔休息时间为1分钟（latpulldown，肩部按压和双侧膝关节伸展）。在WR方案中，受试者完成与NR方案相同的方案，但在每组运动的中点休息30秒，以减少运动引起的代谢应激。两种方案的急性激素反应进行了测量，随后进行了为期12周的阻力训练。结果如下：NR和WR方案后血乳酸和血清激素浓度的测量结果表明，NR方案诱导了强烈的乳酸，生长激素（GH），肾上腺素（E）和去甲肾上腺素（NE）的反应，而WR方案没有。两种方案均未能引起睾酮的显著变化。12 wk后，NR组的伸膝肌力（P < 0.01）、最大等长肌力（P < 0.05）和肌耐力（P < 0.05）均显著高于WR组。NR组肌肉横截面积显著增加（P < 0.01），而WR组和CON组无显著变化。结论：这些结果表明，运动诱导的代谢应激与急性GH，E和NE反应和慢性肌肉适应后的阻力训练。
Purpose: The purpose of this study was to examine the impact of exercise-induced metabolic stress on hormonal responses and chronic Muscular adaptations. Methods: We compared the acute and long-term effects of an "NR regimen" (no-rest regimen) and those of a "WR regimen" (regimen with rest period within a set). Twenty-six male subjects were assigned to either the NR (N = 9), WR (N = 9), or control (CON, N = 8) groups. The NR regimen consisted of 3-5 sets of 10 repetitions at 10-repetition maximum (RM) with an interset rest period of I min (lat pulldown, shoulder press, and bilateral knee extension). In the WR regimen, subjects completed the same protocol as the NR regimen, but took a 30-s rest period at the midpoint of each set of exercises in order to reduce exercise-induced metabolic stress. Acute hormonal responses to both regimens were measured followed by a 12-wk period of resistance training. Results: Measurements of blood lactate and serum hormone concentrations after the NR and WR regimens showed that the NR regimen induced strong lactate, growth hormone (GH), epinephrine (E), and norepinephrine (NE) responses, whereas the WR regimen did not. Both regimens failed to cause significant changes in testosterone. After 12 wk of resistance training, the NR regimen caused greater increases in IRM (P < 0.01), maximal isometric strength (P < 0.05), and muscular endurance (P < 0.05) with knee extension than the WR regimen. The NR group showed a marked increase (P < 0.01) in muscle cross-sectional area, whereas the WR and CON groups did not. Conclusion: These results suggest that exercise-induced metabolic stress is associated with acute GH, E, and NE responses and chronic muscular adaptations following resistance training.