Peroxisome proliferator‐activated receptor delta protects against obesity‐related glomerulopathy through the P38 MAPK pathway
Peroxisome proliferator‐activated receptor delta protects against obesity‐related glomerulopathy through the P38 MAPK pathway
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DOI：
10.1002/oby.20103
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发表时间：
2013-03
期刊：
影响因子：
6.9
通讯作者：
Zhencheng Yan;Yinxing Ni;Peijian Wang;Jian Chen;Hong-bo He;Jing Sun;T. Cao;Jing Chen;Zhigang Zhao;Zhidan Luo;Lina Chen;Daoyan Liu;Zhiming Zhu
中科院分区：
文献类型：
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作者：
Zhencheng Yan;Yinxing Ni;Peijian Wang;Jian Chen;Hong-bo He;Jing Sun;T. Cao;Jing Chen;Zhigang Zhao;Zhidan Luo;Lina Chen;Daoyan Liu;Zhiming Zhu
肥胖是代谢综合征的重要组成部分，也是肾脏疾病的主要危险因素。本研究旨在探讨过氧化物酶体增殖物激活受体（PPAR）δ和p38丝裂原活化蛋白激酶（p38 MAPK）之间的相互作用在肥胖相关性肾小球病中的作用。
Obesity is a prominent component of metabolic syndrome and a major risk factor for renal disease. The aim of this study was to explore the effect of cross‐talk between peroxisome proliferator‐activated receptor (PPAR)δ and p38 mitogen‐activated protein kinase (p38 MAPK) on obesity‐related glomerulopathy.