Estimation of internal uterine pressure by joint amplitude and frequency analysis of electrohysterographic signals
Estimation of internal uterine pressure by joint amplitude and frequency analysis of electrohysterographic signals
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DOI：
10.1088/0967-3334/29/7/011
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发表时间：
2008-07-01
影响因子：
3.2
通讯作者：
Bergmans, Jan W. M.
中科院分区：
文献类型：
--
作者：
Rabotti, Chiara;Mischi, Massimo;Bergmans, Jan W. M.
在妊娠和分娩期间监测子宫收缩可提供重要的预后信息。临床实践中采用的现有方法在可靠性和侵入性之间进行了折衷。子宫电图法是一种很有前途的子宫收缩监测技术。EHG信号测量触发子宫肌肉收缩的电活动。提出了一种基于EHG信号分析的无创宫内压(IUP)估计方法。认为EHG信号是一种非平稳信号，其频率和幅度特性与IUP有关。因此，在多通道配置中捕获之后，EHG信号在时频域中被分析。然后通过计算频谱的非归一化第一统计矩来推导出IUP的第一估计。最后，通过辨识一个二阶多项式模型，提高了估计精度。将所提出的方法与均方根分析和最优线性滤波进行了比较，并通过同时测量9名产妇的IUP来验证该方法的有效性。结果表明，所提出的EHG信号分析提供了对IUP的准确估计。
Monitoring the uterine contraction provides important prognostic information during pregnancy and parturition. The existing methods employed in clinical practice impose a compromise between reliability and invasiveness. A promising technique for uterine contraction monitoring is electrohysterography (EHG). The EHG signal measures the electrical activity which triggers the contraction of the uterine muscle. In this paper, a non-invasive method for intrauterine pressure (IUP) estimation by EHG signal analysis is proposed. The EHG signal is regarded as a non-stationary signal whose frequency and amplitude characteristics are related to the IUP. After acquisition in a multi-channel configuration, the EHG signal is therefore analyzed in the time-frequency domain. A first estimation of the IUP is then derived by calculation of the unnormalized first statistical moment of the frequency spectrum. The estimation accuracy is finally increased by identification of a second-order polynomial model. The proposed method is compared to root mean squared analysis and optimal linear filtering and validated by simultaneous measurement of the IUP on nine women during labor. The results suggest that the proposed EHG signal analysis provides an accurate estimate of the IUP.