The N-terminal arms of λ repressor wrap around the operator DNA

The N-terminal arms of λ repressor wrap around the operator DNA
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λ 阻遏物的 N 端臂包裹操纵基因 DNA

DOI:
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发表时间:
1982
期刊:
影响因子:
64.8
通讯作者:
R. Sauer
R. Sauer
中科院分区:
综合性期刊1区
文献类型:
--
作者:
C. Pabo;W. Krovatin;A. Jeffrey;R. Sauer

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从λ阻遏物片段保护操纵基因碱基不受化学修饰的能力差异来看,我们认为λ阻遏物的前几个N-末端残基形成了一个延伸臂,当阻遏物与操纵基因结合时,延伸臂延伸到DNA螺旋的后部。
From differences in the ability of fragments of the λ repressor to protect operator bases from chemical modification we suggest that the first few N-terminal residues of the λ repressor form an extended arm that reaches around the back of the DNA helix when repressor binds to the operator.