PATHOLOGY OF AMYOTROPHIC LATERAL SCLEROSIS: FIBER ANALYSIS OF THE VENTRAL ROOTS AND PYRAMIDAL TRACTS OF THE SPINAL CORD
PATHOLOGY OF AMYOTROPHIC LATERAL SCLEROSIS: FIBER ANALYSIS OF THE VENTRAL ROOTS AND PYRAMIDAL TRACTS OF THE SPINAL CORD
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肌萎缩侧索硬化症的病理学：脊髓腹根和锥体束的纤维分析
DOI：
10.1001/archneurpsyc.1941.02280230025003
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发表时间：
1941
影响因子：
1.9
通讯作者：
R. Swank
中科院分区：
文献类型：
--
作者：
G. Wohlfart;R. Swank
Kure和合作者1和Hechst 2提出，在肌萎缩侧索硬化症的病例中，只有前根中的大神经纤维退化，而小纤维保持完整。Kure说，锥体束和红核脊髓束也是如此。由于这些观察没有得到测量的支持，而且材料有限，他们的陈述几乎没有得到认可。马尔堡3认为，库尔和赫希斯特的观察并没有证明前根中有一个特殊的纤维系统保持完整，因为其他研究者在他们的病例中没有注意到前根中大纤维的主要损失，并提出这些小纤维是萎缩的。Karlstrom和Wohlfart4报道，在婴儿脊髓肌肉萎缩症的病例中，前根中的大神经纤维数量明显减少，
It has been suggested (Kure and collaborators 1 and Hechst 2 ) that only the large nerve fibers in the ventral roots degenerate in cases of amyotrophic lateral sclerosis and that the small fibers remain intact. Kure stated that this was true of the pyramidal and rubrospinal tracts as well. As these observations were not supported by measurements and the material was limited, their statements have received little recognition. Marburg 3 expressed the belief that the observations of Kure and Hechst did not prove that a special fiber system was left intact in the ventral roots, since other investigators had not noted a predominant loss of large fibers in the ventral roots in their cases, and suggested as an alternative that these small fibers were atrophic. Karlstrom and Wohlfart 4 reported a marked reduction in the number of large nerve fibers in the ventral roots in cases of infantile spinal muscular