Development of design methods for a centrifugal blood pump with a fluid dynamic approach: results in hemolysis tests.
Development of design methods for a centrifugal blood pump with a fluid dynamic approach: results in hemolysis tests.
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采用流体动力学方法开发离心血泵的设计方法：溶血测试结果。
DOI：
10.1046/j.1525-1594.1999.06417.x
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发表时间：
1999
影响因子：
2.4
通讯作者：
Y. Konishi
中科院分区：
文献类型：
--
作者：
T. Masuzawa;T. Tsukiya;S. Endo;E. Tatsumi;Y. Taenaka;H. Takano;T. Yamane;M. Nishida;B. Asztalos;Y. Miyazoe;K. Ito;T. Sawairi;Y. Konishi
本研究的目的是通过整合溶血试验、流动可视化和计算流体动力学来检查局部流动条件与溶血水平之间的关系，以建立具有较低溶血水平的离心血泵的实用设计标准。Nikkiso离心血泵被用作标准模型，并对具有3个几何参数的不同值的泵进行了测试。所研究的参数是叶轮叶片的外缘与壳体壁之间的径向间隙、出口端口的位置和叶轮叶片的排出角。就Nikkiso离心血泵而言，窄径向间隙对溶血的影响与没有证据表明出口位置或叶片排放角度影响血液创伤一致。为减少血液损伤，应将径向间隙作为离心血泵的设计参数。
The purpose of this study was to examine the relationship between local flow conditions and the hemolysis level by integrating hemolysis tests, flow visualization, and computational fluid dynamics to establish practical design criteria for centrifugal blood pumps with lower levels of hemolysis. The Nikkiso centrifugal blood pump was used as a standard model, and pumps with different values of 3 geometrical parameters were tested. The studied parameters were the radial gap between the outer edge of the impeller vane and the casing wall, the position of the outlet port, and the discharge angle of the impeller vane. The effect of a narrow radial gap on hemolysis was consistent with no evidence that the outlet port position or the vane discharge angle affected blood trauma in so far as the Nikkiso centrifugal blood pump was concerned. The radial gap should be considered as a design parameter of a centrifugal blood pump to reduce blood trauma.