Dietary intervention as a therapeutic for cancer.

Dietary intervention as a therapeutic for cancer.
复制标题

DOI:
10.1111/cas.14777
复制
发表时间:
2021-03
期刊:
影响因子:
5.7
通讯作者:
Tanuma N
Tanuma N
中科院分区:
医学2区
文献类型:
--
作者:
Morita M;Kudo K;Shima H;Tanuma N

文献摘要

参考文献

被引文献

相似文献

癌症新陈代谢受微环境中营养素可用性的影响,并在一定程度上可以通过针对致癌新陈代谢的饮食调整来控制。到目前为止,很少有饮食干预被科学证明可以减缓人类癌症的疾病进展或增强任何其他类型的治疗。然而,最近在了解癌症代谢方面的进展使我们能够预测或设计有效的饮食干预措施,可能会对抗肿瘤的生长。事实上,来自临床前模型的证据表明,特定癌症治疗与饮食干预的适当组合可能会严重影响治疗效果。在这里,我们回顾了精确营养方法在提高癌症治疗效果方面的潜在好处。在了解癌症代谢方面的最新进展使我们能够预测或设计有效的饮食干预措施,可能会对抗肿瘤的生长。事实上,来自临床前模型的证据表明,特定癌症治疗与饮食干预的适当组合可能会严重影响治疗效果。
Cancer metabolism is influenced by availability of nutrients in the microenvironment and can to some extent be manipulated by dietary modifications that target oncogenic metabolism. As yet, few dietary interventions have been scientifically proven to mitigate disease progression or enhance any other kind of therapy in human cancer. However, recent advances in the understanding of cancer metabolism enable us to predict or devise effective dietary interventions that might antagonize tumor growth. In fact, evidence emerging from preclinical models suggests that appropriate combinations of specific cancer therapies with dietary interventions could critically impact therapeutic efficacy. Here, we review the potential benefits of precision nutrition approaches in augmenting the efficacy of cancer treatment. Recent advances in the understanding of cancer metabolism enable us to predict or devise effective dietary interventions that might antagonize tumor growth. In fact, evidence emerging from preclinical models suggests that appropriate combinations of specific cancer therapies with dietary interventions could critically impact therapeutic efficacy.
DOI: 10.1016/j.cmet.2015.05.012
发表时间: 2015-07-07
期刊: Cell metabolism
影响因子: 29
作者:
Brandhorst S;Choi IY;Wei M;Cheng CW;Sedrakyan S;Navarrete G;Dubeau L;Yap LP;Park R;Vinciguerra M;Di Biase S;Mirzaei H;Mirisola MG;Childress P;Ji L;Groshen S;Penna F;Odetti P;Perin L;Conti PS;Ikeno Y;Kennedy BK;Cohen P;Morgan TE;Dorff TB;Longo VD
通讯作者: Longo VD
DOI: 10.1038/nature22314
发表时间: 2017-05-25
期刊: Nature
影响因子: 64.8
作者:
Hattori A;Tsunoda M;Konuma T;Kobayashi M;Nagy T;Glushka J;Tayyari F;McSkimming D;Kannan N;Tojo A;Edison AS;Ito T
通讯作者: Ito T
DOI: 10.1038/nm.4232
发表时间: 2017-01
期刊: Nature medicine
影响因子: 82.9
作者:
通讯作者: --
DOI: 10.1016/j.ccr.2011.01.038
发表时间: 2011-03-15
期刊: CANCER CELL
影响因子: 50.3
作者:
Ishimoto, Takatsugu;Nagano, Osamu;Saya, Hideyuki
通讯作者: Saya, Hideyuki
DOI: 10.1038/s41586-018-0316-7
发表时间: 2018-07
期刊: Nature
影响因子: 64.8
作者:
Kanarek N;Keys HR;Cantor JR;Lewis CA;Chan SH;Kunchok T;Abu-Remaileh M;Freinkman E;Schweitzer LD;Sabatini DM
通讯作者: Sabatini DM