THE INVOLVEMENT OF MONKEY PREMOTOR CORTEX NEURONS IN PREPARATION OF VISUALLY CUED ARM MOVEMENTS
THE INVOLVEMENT OF MONKEY PREMOTOR CORTEX NEURONS IN PREPARATION OF VISUALLY CUED ARM MOVEMENTS
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DOI：
10.1016/0166-4328(85)90070-1
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发表时间：
1985-11-01
影响因子：
2.7
通讯作者：
VANDERSTEEN, J
中科院分区：
文献类型：
--
作者：
GODSCHALK, M;LEMON, RN;VANDERSTEEN, J
猕猴星后运动前区的某些神经元在需要视觉信息的运动任务中调节其放电频率。我们以前报告说，这些神经元的很大一部分调制在执行绕道到达任务，其中的运动阶段是分开的时间，在该阶段中，猴子收到的视觉提示所需的运动检索食物奖励。大部分与任务相关的神经元（75%）在这个“视觉”阶段进行调制，其中没有与任务相关的运动。这种调制与食物奖励的位置有关，这是视觉线索。这些神经元大多数位于皮质区6，接近弓状弯曲和它的马刺，但也更尾部在4区和喙部在8区。在目前的猴子慢性记录实验中，原始任务的几种变化被用来测试与“视觉”相关的神经元调制是否参与了即将到来的运动的准备。这种调制不太可能与视觉阶段发生的任何眼睛或手臂运动或环境照明的变化有关。它也不能与视觉线索在视野的特定部分的存在有关，因为当使用具有固定位置的线索时，神经元调制的模式是相似的。然而，这种调制是，在随后的“运动阶段”的食物检索的发生，因为它被取消或减少在介绍的“食物奖励”，猴子没有检索。对于几个神经元，在视觉阶段的调制模式取决于食物奖励是通过粗略的手部运动还是相对独立的手指运动来获取。因此，在视觉线索的帮助下，后足前运动皮层的神经元可能参与了手臂运动的准备。本文从皮质-皮质通路的角度讨论了视觉信息从视区经顶叶联合区和运动前皮层到初级运动皮层的传递。
Some neurons in macaque postarcuate premotor area modulate their firing frequency in relation to motor tasks which require visual information. We previously reported that a large proportion of these neurons modulate during execution of a detour reaching task in which the movement phase was separated in time from the phase in which the monkey received a visual cue for the movement required to retrive a food reward. A large proportion of task-related neurons (75%) modulated during this ''visual'' phase, in which no task-related movements were made. This modulation was related to the position of the food reward, which served as the visual cue. Most of these neurones were located in cortical area 6, close to the arcuate curvature and its spur, but also more caudally in area 4 and rostrally in area 8. In the present chronic recording experiments in monkeys, several variations of the original task were used in order to test whether the ''visual''-related neuronal modulation could be involved in preparation of the upcoming movement. This modulation is unlikely to be related to any eye or arm movements occurring during the visual phase or to changes in environmental illumination. Neither can it be related to the presence of the visual cue in a particular part of the visual field, since the pattern of neuronal modulation was similar when a cue with a fixed position was used. This modulation was, however, contingent upon the occurrence of food retrieval during the subsequent ''movement phase'', since it was abolished or diminished during presentation of a ''food-reward'' which the monkey did not retrieve. For several neurones, modulation pattern during the visual phase depended on whether the food rewards was to be retrieved with a gross hand movement or with relatively independnet finger movements. It is likely, therefore, that neurons in the postarcuate premotor cortex are involved in preparation for arm movements with the help of visual cues. The results are discussed in view of corticocortical pathway which might be involved in transmission of visual information from visual areas through parietal association areas and premotor cortex to the primary motor cortex.