Simultaneous MR thermometry and acoustic radiation force imaging using interleaved acquisition
Simultaneous MR thermometry and acoustic radiation force imaging using interleaved acquisition
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DOI：
10.1002/mrm.26827
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发表时间：
2018-03-01
影响因子：
3.3
通讯作者：
Parker, Dennis L.
中科院分区：
文献类型：
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作者：
de Bever, Joshua T.;Odeen, Henrik;Parker, Dennis L.
目的提出一种同时进行磁共振声辐射力成像（ARFI）和质子共振频移测温的新方法。这可能是一个重要的工具，用于评估成功的MR引导下的聚焦超声程序，MR测温测量温度和热剂量和MR-ARFI检测组织的机械properties.MethodsMR成像的变化进行使用梯度召回回波分段回波平面成像脉冲序列与双极运动编码梯度（MEG）。在MEG期间，在重复时间（TR）水平上交错具有超声脉冲（ON）和不具有超声脉冲（OFF）的图像。ARFI位移通过ON-OFF图像的复数减影计算，PRF温度图通过基线减影计算。在组织模拟体模和离体猪脑组织中进行评价。约束重建提高了动态测量的时间分辨率。结果在保持组织加热的同时，以2D和3D方式同时获取位移和温度图
PurposeA novel and practical method for simultaneously performing MR acoustic radiation force imaging (ARFI) and proton resonance frequency (PRF)-shift thermometry has been developed and tested. This could be an important tool for evaluating the success of MR-guided focused ultrasound procedures for which MR-thermometry measures temperature and thermal dose and MR-ARFI detects changes in tissue mechanical properties.MethodsMR imaging was performed using a gradient recalled echo segmented echo-planar imaging pulse sequence with bipolar motion encoding gradients (MEG). Images with ultrasound pulses (ON) and without ultrasound pulses (OFF) during the MEG were interleaved at the repetition time (TR) level. ARFI displacements were calculated by complex subtraction of ON-OFF images, and PRF temperature maps were calculated by baseline subtraction. Evaluations in tissue-mimicking phantoms and ex vivo porcine brain tissue were performed. Constrained reconstruction improved the temporal resolution of dynamic measurements.ResultsSimultaneous maps of displacement and temperature were acquired in 2D and 3D while keeping tissue heating