Secondary use of clinical data: The Vanderbilt approach
Secondary use of clinical data: The Vanderbilt approach
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DOI：
10.1016/j.jbi.2014.02.003
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发表时间：
2014-12-01
影响因子：
4.5
通讯作者：
Harris, Paul A.
中科院分区：
文献类型：
--
作者：
Danciu, Ioana;Cowan, James D.;Harris, Paul A.
在过去的十年中，全国范围内收集的临床数据数量呈指数级增长，这引发了将这些数据重新用于生物医学研究的机会增加。范德比尔特研究数据仓库框架包括已识别和去识别的临床数据存储库、按服务收费的定制服务，以及构建在数据层之上的工具，以帮助整个企业的研究人员。为研究项目提供资源不仅有利于研究界，也有利于临床医生、患者和机构领导。这项工作总结了我们在研究领域中二次使用临床数据的方法，包括对关键组件的描述和经验教训的列表，旨在帮助其他人组装类似的服务和基础设施。(C) 2014爱思唯尔公司版权所有。
The last decade has seen an exponential growth in the quantity of clinical data collected nationwide, triggering an increase in opportunities to reuse the data for biomedical research. The Vanderbilt research data warehouse framework consists of identified and de-identified clinical data repositories, fee-for-service custom services, and tools built atop the data layer to assist researchers across the enterprise. Providing resources dedicated to research initiatives benefits not only the research community, but also clinicians, patients and institutional leadership. This work provides a summary of our approach in the secondary use of clinical data for research domain, including a description of key components and a list of lessons learned, designed to assist others assembling similar services and infrastructure. (C) 2014 Elsevier Inc. All rights reserved.