EMCCD-based photon-counting mini gamma camera with a spatial resolution < 100 /spl mu/m
EMCCD-based photon-counting mini gamma camera with a spatial resolution < 100 /spl mu/m
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基于 EMCCD 的光子计数迷你伽玛相机，空间分辨率 < 100 /spl mu/m
DOI：
10.1109/nssmic.2004.1466253
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
F. Beekman
中科院分区：
文献类型：
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作者：
G.A. de Vree;F. van der Have;F. Beekman
具有高固有空间分辨率和光子计数能力的紧凑型伽马相机对于天文学、生物学和医学中的若干应用是非常理想的。在这里，我们提出了一种新的光子计数伽马相机，是基于电子倍增CCD（EMCCD）。实际上，EMCCD具有子电子读出噪声，即使在每秒50帧时。这种高帧速率允许分析关于能量和位置的个体闪烁事件。在我们的相机中，EMCCD是Peltier冷却和光纤锥CsI（Tl）柱状晶体层安装在它上面。通过冷却CCD到-30 ℃，暗电流噪声可以忽略不计。本征分辨率使用线形伽马束测定，并且对于Co-57和I-125两者均优于100微米FWHM。我们的结论是，EMCCD与柱状晶体相结合，可以构建极高分辨率的光子计数伽马相机，适用于针孔SPECT
Compact gamma cameras with high intrinsic spatial resolution and photon counting capabilities are very desirable for several applications in astronomy, biology and medicine. Here we present a novel photon-counting gamma camera that is based on an Electron-multiplying CCD (EMCCD). Effectively, the EMCCD has sub-electron read out noise, even at 50 frames per second. This high frame rate allows for analyzing individual scintillation events with respect to energy and position. In our camera, the EMCCD is Peltier cooled and a fiber optic taper with a CsI(Tl) columnar crystal layer are mounted on it. By cooling the CCD to -30 degC, dark current noise is negligible. Intrinsic resolution was determined using a line shaped gamma beam, and was better than 100 microns FWHM for both Co-57 and I-125. We conclude that EMCCDs combined with columnar crystals allow for constructing extremely high-resolution photon counting gamma cameras, which are suitable for pinhole SPECT
用于三维脑成像的固定半球形 SPECT 成像仪。
DOI：
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发表时间：
1993
期刊：
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子：
--
作者：
Rowe,RK;Aarsvold,JN;Barrett,HH;Chen,JC;Klein,WP;Moore,BA;Pang,IW;Patton,DD;White,TA
通讯作者：
White,TA