Psychiatric and substance use disorders as risk factors for low birth weight and preterm delivery
Psychiatric and substance use disorders as risk factors for low birth weight and preterm delivery
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DOI：
10.1016/s0029-7844(02)02014-8
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发表时间：
2002-08-01
影响因子：
7.2
通讯作者：
Katon, W
中科院分区：
文献类型：
--
作者：
Kelly, RH;Russo, J;Katon, W
目的：我们调查了1995年在加州医院分娩的所有产妇中精神疾病和药物使用诊断与低出生体重(LBW)、极低出生体重(VLBW)和早产的关系。方法：这项基于人群的回顾性队列分析使用了521,490例分娩的出院和出生证明数据。在控制母亲的人口学和医学特征的同时，采用Logistic回归分析来评估母亲精神疾病和药物使用出院诊断与LBW、VLBW和早产的关系。结果：有精神疾病诊断的女性发生LBW(调整后的优势比[OR]2.0；95%可信区间[CI]1.7、23)、VLBW(OR 2.9；95%CI 2.1、3.9)和早产的风险显著增加。分娩(OR 1.6；95%CI 1.4，1.9)与没有这些诊断的妇女相比。药物滥用诊断与低出生体重儿(OR 3.7；95%CI 3.4，4.0)、极低出生体重(OR 2.8；95%CI 2.3，3.3)和早产(OR 2.4；95%CI 2.3，2.6)的风险增加有关。结论：母亲精神疾病和药物滥用诊断与低出生体重和早产独立相关。1995年在加利福尼亚州分娩的妇女人口中的分娩情况。在这一人群中识别患有当前精神障碍的孕妇并加强对早产和低出生体重分娩的监测可能是必要的。(C)2002年，由美国妇产科医师学会提供。
OBJECTIVE: We examined the associations between psychiatric and substance use diagnoses and low birth weight (LBW, very low birth weight (VLBW), and preterm delivery among all women delivering in California hospitals during 1995.METHODS: This population-based retrospective cohort analysis used linked hospital discharge and birth certificate data for 521,490 deliveries. Logistic regression analyses were conducted to assess the associations between maternal psychiatric and substance use hospital discharge diagnoses and LBW, VLBW, and preterm delivery while controlling for maternal demographic and medical characteristics.RESULTS: Women with psychiatric diagnoses had a significantly higher risk of LBW (adjusted odds ratio [OR] 2.0; 95% confidence interval [CI] 1.7,23), VLBW (OR 2.9; 95% Cl 2.1, 3.9), and preterm. delivery (OR 1.6; 95% Cl 1.4, 1.9) compared with women without those diagnoses. Substance use diagnoses were also associated with higher risk of LBW (OR 3.7; 95% Cl 3.4,4.0), VLBW (OR 2.8; 95% CI 2.3,3.3), and preterm, delivery (OR 2.4; 95% CI 2.3, 2.6).CONCLUSION: Maternal psychiatric and substance use diagnoses were independently associated with low birth weight and preterm. delivery in the population of women delivering in California in 1995. Identifying pregnant women with current psychiatric disorders and increased monitoring for preterm and low birth weight delivery among this population may be indicated. (C) 2002 by The American College of Obstetricians and Gynecologists.