Changing dynamics of the drug overdose epidemic in the United States from 1979 through 2016.

Changing dynamics of the drug overdose epidemic in the United States from 1979 through 2016.
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DOI:
10.1126/science.aau1184
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发表时间:
2018-09-21
期刊:
Science (New York, N.Y.)
影响因子:
--
通讯作者:
Burke DS
Burke DS
中科院分区:
其他
文献类型:
--
作者:
Jalal H;Buchanich JM;Roberts MS;Balmert LC;Zhang K;Burke DS

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更好地了解当前美国药物过量流行的动态可能有助于制定更有效的预防和控制策略。我们分析了1979年至2016年来自国家生命统计系统的599255例死亡记录,其中意外药物中毒被确定为主要死因。通过检查1979年以来所有关于意外中毒死亡的现有数据,并表明38年的总体曲线是指数型的,我们提供的证据表明,当前阿片类药物过量死亡浪潮(由处方阿片类药物、海洛因和芬太尼导致)可能只是一个更基本的长期过程的最新表现。美国年度意外药物中毒总死亡人数38年多的平滑指数曲线是不同药物(主要是处方阿片类药物、海洛因、美沙酮、合成阿片类药物、可卡因和甲基苯丙胺)的多个独特亚流行的综合,每种药物都有其自身特定的人口统计学和地理特征。 美国药物过量流行的动态正在发生变化
Better understanding of the dynamics of the current US overdose epidemic may aid in the development of more effective prevention and control strategies. We analyzed records of 599,255 deaths from 1979 through 2016 from the National Vital Statistics System in which accidental drug poisoning was identified as the main cause of death. By examining all available data on accidental poisoning deaths back to 1979 and showing that the overall 38-year curve is exponential, we provide evidence that the current wave of opioid overdose deaths (due to prescription opioids, heroin, and fentanyl) may just be the latest manifestation of a more fundamental longer term process. The 38+ year smooth exponential curve of total US annual accidental drug poisoning deaths is a composite of multiple distinctive sub-epidemics of different drugs (primarily prescription opioids, heroin, methadone, synthetic opioids, cocaine, and methamphetamine), each with its own specific demographic and geographic characteristics. USA overdose epidemic dynamics are changing
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