Measurement of the force required to move a neurosurgical probe through in vivo human brain tissue
Measurement of the force required to move a neurosurgical probe through in vivo human brain tissue
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DOI：
10.1109/10.771205
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发表时间：
1999-07-01
影响因子：
4.6
通讯作者：
Gillies, GT
中科院分区：
文献类型：
--
作者：
Howard, MA;Abkes, BA;Gillies, GT
随着高精度磁性和机器人计算机控制神经外科系统的出现，有必要确定此类设备的探头在被引导通过脑组织到达实质内靶点时将遇到的力的范围。我们测量了2.5 mm球体上的穿透力和3.0 mm脑室分流管上2.0-3.5 cm深进入活体人脑组织的阻力，接近0.33 mm S(-1)的速率。球形探头在穿过大脑皮层表面下0.5 cm处的穿透力为(8+/-2)克，在导管上施加(2.8+/-0.3)克/厘米(-1)的摩擦力，讨论了这些力的变化特性，并与早期对动物组织和脑模型明胶的研究结果进行了比较。考虑了这些结果对磁性和机器人手术系统的影响。
The advent of high-precision magnetic and robotic computer-controlled neurosurgery systems makes it necessary to determine the range of forces that will be encountered by the probes of such devices as they are guided through the brain tissues to intraparenchymal targets. We have measured the penetration forces on 2.5-mm spheres and the drag forces on 3.0-mm ventricular shunt catheters advanced 2.0-3.5 cm deep into in vivo human brain tissues tin patients about to have those tissues resected during epilepsy surgery) at rates of approximate to 0.33 mm s(-1). Penetration forces of (8 +/- 2) grams were found for the spherical probe once it passed 0.5 cm below the cortical surface, and frictional drags of (2.8 +/- 0.3) grams cm(-1) were exerted on the catheters, The variable nature of these forces is discussed and the results are compared with earlier studies on experimental animal tissues and brain phantom gelatins. The implications of these results for magnetic and robotic surgery systems are considered.