Acidosis and nutritional status in hemodialyzed patients
Acidosis and nutritional status in hemodialyzed patients
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DOI：
10.1046/j.1525-139x.2000.00066.x
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发表时间：
2000-07-01
影响因子：
1.6
通讯作者：
Leverve, X
中科院分区：
文献类型：
--
作者：
Chauveau, P;Fouque, D;Leverve, X
在一项针对超过30%的法国透析患者（N = 7，123）的横断面研究中，我们评估了透析前血浆碳酸氢盐浓度与营养标志物之间的关系。收集的数据包括年龄、性别、终末期肾病（ESRD）的病因、透析时间、体重指数（BMI）、周中透析前白蛋白、前白蛋白和碳酸氢盐的血液水平。根据Garred的经典公式，根据碳酸氢盐透析前后的尿素和肌酐水平计算标准化蛋白质分解代谢率（nPCR）、透析充分性参数和瘦体重（LBM）估计值。平均值（± 1 SD）为年龄61 ± 16岁，BMI 23.3 ± 4.6 kg/m2，透析时间12.4 ± 2.7 h/周，HCO 3 22.8 ± 3.5 mmol/L，白蛋白38.7 ± 5.3 g/L，前白蛋白340 ± 90 mg/L。
In a cross-sectional study of more than 30% of French dialysis patients (N = 7,123), we evaluated the relationships between predialysis plasma bicarbonate concentration and nutritional markers. Data including age, gender, cause of end-stage renal disease (ESRD), time on dialysis, body mass index (BMI), blood levels of midweek predialysis albumin, prealbumin, and bicarbonate were collected. Normalized protein catabolic rate (nPCR), dialysis adequacy parameters, and estimation of lean body mass (LBM) were computed from pre- and postbicarbonate-dialysis urea and creatinine levels according to the classical formulas of Garred. Average values (+/-1 SD) were age 61 +/- 16 years, BMI 23.3 +/- 4.6 kg/m(2), dialysis time 12.4 +/- 2.7 h/week, HCO3 22.8 +/- 3.5 mmol/L, albumin 38.7 +/- 5.3 g/L, prealbumin 340 +/- 90 mg/L.