Glucose kinetics and substrate oxidation during exercise in the follicular and luteal phases.
Glucose kinetics and substrate oxidation during exercise in the follicular and luteal phases.
复制标题
卵泡期和黄体期运动期间的葡萄糖动力学和底物氧化。
DOI：
10.1152/jappl.2001.90.2.447
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发表时间：
2001
期刊：
影响因子：
--
通讯作者：
Ruby,BC
中科院分区：
文献类型：
--
作者：
Zderic,TW;Coggan,AR;Ruby,BC
The purpose of this investigation was to determine whether plasma glucose kinetics and substrate oxidation during exercise are dependent on the phase of the menstrual cycle. Once during the follicular (F) and luteal (L) phases, moderately trained subjects [peak O2uptake (V˙o2) = 48.2 ± 1.1 ml · min−1· kg−1;n= 6] cycled for 25 min at ∼70% of theV˙o2at their respective lactate threshold (70%LT), followed immediately by 25 min at 90%LT. Rates of plasma glucose appearance (Ra) and disappearance (Rd) were determined with a primed constant infusion of [6,6-2H]glucose, and total carbohydrate (CHO) and fat oxidation were determined with indirect calorimetry. At rest and during exercise at 70%LT, there were no differences in glucose Raor Rdbetween phases. CHO and fat oxidation were not different between phases at 70%LT. At 90%LT, glucose Ra(28.8 ± 4.8 vs. 33.7 ± 4.5 μmol · min−1· kg−1;P< 0.05) and Rd(28.4 ± 4.8 vs. 34.0 ± 4.1 μmol · min−1· kg−1;P< 0.05) were lower during the L phase. In addition, at 90%LT, CHO oxidation was lower during the L compared with the F phase (82.0 ± 12.3 vs. 93.8 ± 9.7 μmol · min−1· kg−1;P< 0.05). Conversely, total fat oxidation was greater during the L phase at 90%LT (7.46 ± 1.01 vs. 6.05 ± 0.89 μmol · min−1· kg−1;P< 0.05). Plasma lactate concentration was also lower during the L phase at 90%LT concentrations (2.48 ± 0.41 vs. 3.08 ± 0.39 mmol/l;P< 0.05). The lower CHO utilization during the L phase was associated with an elevated resting estradiol (P< 0.05). These results indicate that plasma glucose kinetics and CHO oxidation during moderate-intensity exercise are lower during the L compared with the F phase in women. These differences may have been due to differences in circulating estradiol.
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DOI：
10.1016/s0021-9258(17)44316-x
发表时间：
1983-10
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
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DOI：
10.1016/s0021-9258(19)41818-8
发表时间：
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期刊：
The Journal of biological chemistry
影响因子：
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作者：
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作者：
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影响因子：
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