ENZYME CHANGES IN FLIGHT MUSCLE CORRELATED WITH AGING AND FLIGHT ABILITY IN MALE HOUSEFLY
ENZYME CHANGES IN FLIGHT MUSCLE CORRELATED WITH AGING AND FLIGHT ABILITY IN MALE HOUSEFLY
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DOI：
10.1126/science.139.3559.1049
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发表时间：
1963-01-01
期刊：
影响因子：
56.9
通讯作者：
BRANDT, KF
中科院分区：
文献类型：
--
作者：
ROCKSTEIN, M;BRANDT, KF
衰老雄性家蝇飞行肌的巨型线粒体（肌小体）中镁激活的三磷酸腺苷酶活性随着飞行失败而降低，这反映在成虫第二周翅膀的丧失。然而，在失去翅膀之前，α-甘油磷酸脱氢酶的活性迅速下降，该酶位于线粒体外部分并依赖于烟酰胺腺嘌呤二核苷酸。
Magnesium-activated adenosine triphosphatase activity in the giant mitochondria (sarcosomes) of the flight muscle of aging male houseflies decreases concomitantly with failure in flight as reflected in the loss of wings during the second week of adult life. Preceding the loss of wings, however, there is a rapid decline in the activity of an a-glycerophosphate dehydrogenase which is located in the extramitochondrial fraction and is dependent on nicotinamide adenine dinucleotide.