Thermally Stable Honeycomb‐Patterned Porous Films of a Poly(L‐lactic acid) and Poly(D‐lactic acid) Stereo Complex Prepared Using the Breath Figure Technique
Thermally Stable Honeycomb‐Patterned Porous Films of a Poly(L‐lactic acid) and Poly(D‐lactic acid) Stereo Complex Prepared Using the Breath Figure Technique
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DOI：
10.1002/mame.201500474
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发表时间：
2016-05
影响因子：
3.9
通讯作者：
H. Abe;Yutaro Hirai;H. Yabu
中科院分区：
文献类型：
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作者：
H. Abe;Yutaro Hirai;H. Yabu
由可生物降解聚合物制备的多孔聚合物材料因其作为组织工程细胞培养支架的潜力而备受关注。多孔材料通常在用作细胞培养支架之前通过高压灭菌进行灭菌，以避免意外的生物感染。然而，可生物降解聚合物的熔点通常低于高压灭菌所用的温度。本文介绍了由聚L-乳酸(PLLA)和聚D-乳酸(PDLA)组成的蜂窝膜的制备及其热稳定性。研究了紫外光作用下PLLA/PDLA立体复合蜂窝结构薄膜的层次化光化学图案化。
Porous polymer materials prepared from biodegradable polymers have received considerable attention due to their potential as cell culture scaffolds for tissue engineering. Porous materials are generally sterilized by autoclaving prior to use as cell culture scaffolds to avoid unexpected biological infection. However, the melting point of biodegradable polymers is typically lower than the temperature used in autoclave sterilization. Here, the preparation of honeycomb films comprising a poly(L‐lactic acid) (PLLA) and poly(D‐lactic acid) (PDLA) stereo complex is described and their thermal stabilities are evaluated. The hierarchic photochemical patterning of PLLA/PDLA stereo complex honeycomb‐patterned films by UV‐O3treatment is also demonstrated.