COMPARISON OF 3 MM × 3 MM VERSUS 6 MM × 6 MM OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY SCAN SIZES IN THE EVALUATION OF NON-PROLIFERATIVE DIABETIC RETINOPATHY.
COMPARISON OF 3 MM × 3 MM VERSUS 6 MM × 6 MM OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY SCAN SIZES IN THE EVALUATION OF NON-PROLIFERATIVE DIABETIC RETINOPATHY.
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DOI：
10.1097/iae.0000000000001951
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发表时间：
2019-03
期刊：
影响因子：
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通讯作者：
Freeman WR
中科院分区：
文献类型：
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作者：
Ho J;Dans K;You Q;Nudleman ED;Freeman WR
To evaluate the utility of different optical coherence tomography angiography (OCT A) scan protocols in evaluating retinal changes in non-proliferative diabetic retinopathy. Patients were imaged with the RTVue XR Avanti OCT 3×3 mm and 6×6 mm “Angio Retina” scan protocols. Ability to clearly delineate the foveal avascular zone (FAZ), FAZ remodeling, microaneurysms (MA), capillary non-perfusion, motion and doubling artifacts were evaluated. 46 eyes from 27 patients enrolled. 89% of 3×3 mm versus 59% of 6×6 mm scans clearly delineated the FAZ (p= 0.001). 80% of 3×3 mm versus 43% of 6×6 mm scans demonstrated FAZ remodeling (p= 0.0002). MAs were detected by 57% of 6×6 mm and 35% of 3×3 mm scans (p= 0.003). Capillary non-perfusion was detected in 87% of 3×3 scans versus 89% of 6×6 mm scans (p= 0.99). No significant differences were noted in the incidence of artifacts between the scan sizes (motion artifact p= 0.29, doubling artifact p= 0.29). 3×3 mm scan delineated FAZ and remodeling better than 6×6 mm scan, likely due to its higher scan density. 6×6 mm scans detected MAs more readily than 3×3 mm, likely due to its larger scan area. There were utility for both 3×3 mm and 6×6 mm scans when evaluating these patients.
