Viral sponges sequester nucleotide signals to inactivate immunity.

Viral sponges sequester nucleotide signals to inactivate immunity.
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病毒海绵会隔离核苷酸信号以灭活免疫力。

DOI:
10.1016/j.tim.2023.04.004
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发表时间:
2023
影响因子:
15.9
通讯作者:
Kranzusch,PhilipJ
Kranzusch,PhilipJ
中科院分区:
生物学1区
文献类型:
--
作者:
Richmond-Buccola,Desmond;Kranzusch,PhilipJ

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细菌合成特殊的核苷酸信号来控制抗噬菌体防御。两篇论文--由Huting等人撰写。和Jenson等人。--现在发现,噬菌体编码蛋白质“海绵”,隔离环核苷酸免疫信号,使宿主的抗病毒免疫失活。
Bacteria synthesize specialized nucleotide signals to control anti-phage defense. Two papers – by Huiting et al. and Jenson et al. – now reveal that bacteriophages encode protein ‘sponges' that sequester cyclic oligonucleotide immune signals and inactivate host antiviral immunity.