Pulsatile ocular blood flow in primary open-angle glaucoma and ocular hypertension

Pulsatile ocular blood flow in primary open-angle glaucoma and ocular hypertension
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DOI:
10.1016/s0002-9394(03)00717-7
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发表时间:
2003-12-01
影响因子:
4.2
通讯作者:
O'brien, C
O'brien, C
中科院分区:
医学1区
文献类型:
--
作者:
Kerr, A;Nelson, P;O'brien, C

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PURPOSE: To compare pulsatile ocular blood flow measurements in untreated ocular hypertensive (OHT) subjects and primary open,angle glaucoma (POAG) patients.DESIGN: A prospective observational study in an institutional setting. 0 METHODS: A total of 97 subjects were recruited to the study (50 ocular hypertensives, 24 glaucoma patients, and 23 normal subjects)."High-risk" OHT had intraocular pressure (IOP) > 25 mm Hg; "low-risk" OHT had IOP :5 25 mm Hg. Pulsatile ocular blood flow (POBF) measurements were made with a pneumotonometer in sitting, standing, and supine positions. Intraocular pressure was measured with Goldmann tonometry. Twenty-six patients were started on topical treatment to reduce intraocular pressure, and the measurements were repeated at a review visit.RESULTS: Untreated POAG patients and high-risk OHT had reduced POBF (P