Three-dimensional computergraphic analysis of apraxia. Neural representations of learned movement.
Three-dimensional computergraphic analysis of apraxia. Neural representations of learned movement.
复制标题
失用症的三维计算机图形分析。
DOI：
10.1093/brain/113.1.85
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Heilman,KM
中科院分区：
文献类型：
--
作者：
Poizner,H;Mack,L;Verfaellie,M;Rothi,LJ;Heilman,KM
人类的左大脑半球包含的解剖结构不仅专门用于语言，而且还专门用于高阶运动编程。研究这些运动程序本质的一种方法是观察左半球损伤的患者所犯错误的类型。然而，在研究这种特殊的左半球系统（失用症）失败导致的疾病时，一个主要问题是难以获得三维空间运动的客观测量。为此，我们首次对失用症中运动错误的本质进行了三维分析。研究了2名左半球病变的失用受试者和5名匹配的对照受试者。失用被试表现出对运动时间和空间关系的控制障碍，以及运动轨迹中某些空间和时间方面的紧密关系的解耦。此外，失用受试者对远端肌肉组织的使用比近端肌肉组织的使用更受损，这表明在任何学习运动的时空图中都有更多的远端表征。这些数据为左脑半球习得的熟练动作表征的本质提供了进一步的见解。
The left cerebral hemisphere in man contains anatomical structures specialized not only for language but also for higher-order motor programming. One method of studying the nature of these motor programs is by observing the type of errors made by patients who have left hemisphere damage. A major problem, however, in investigating the disorders that result from failure of this specialized left hemisphere system (the apraxias) has been the difficulty in obtaining objective measurement of movement in three-dimensional space. To this end, we provide the first three-dimensional analysis of the nature of movement errors in apraxia. Two apraxic subjects with lesions to the left hemisphere and 5 matched control subjects were studied. The apraxic subjects showed impairments in the control of movement timing and spatial relations, as well as decoupling in the normally tight relation between certain spatial and temporal aspects of their movement trajectories. Further, the use of the distal musculature by apraxic subjects was more impaired than their use of the proximal musculature, suggesting more distal representation in any space-time maps of learned movement. These data provide further insight into the nature of the representations of learned skilled movements in the left cerebral hemisphere.