Influence of Narrow Band Imaging (NBI) Videobronchoscopy on the Assessment of Central Lung Cancer Extension and Therapeutic Decision
Influence of Narrow Band Imaging (NBI) Videobronchoscopy on the Assessment of Central Lung Cancer Extension and Therapeutic Decision
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DOI：
10.3109/07357900902918445
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发表时间：
2009-01-01
影响因子：
2.4
通讯作者：
Antonic, Milan
中科院分区：
文献类型：
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作者：
Zaric, Bojan;Perin, Branislav;Antonic, Milan
目的：与单独使用白色光支气管镜检查（WLB）相比，确定窄带成像（NBI）在评估中心型肺癌肿瘤扩展方面的特异性和敏感性，并评价NBI对肺癌患者治疗决策的可能影响。患者和方法：我们评估了36例疑似肺癌患者。所有患者均接受了WLB，随后进行了NBI支气管镜检查。我们使用了电子支气管镜BF-1 T180和EVIS卢塞拉SPECTRUM处理器。结果如下：NBI评估肿瘤扩散的敏感性、特异性、阳性预测值（PPV）和阴性预测值（NPV）分别为97.8%、85%、93.7%和94.4%; WLB分别为92.3%、60%、69.6%和88.9%。在14例患者中，NBI显示比WLB更广泛的肿瘤（p = 0.0057）。在8例患者中，NBI对治疗决策有显著影响（p = 0.001）。结论：NBI电子支气管镜对中心型肺癌的诊断具有较好的特异性和敏感性，对指导治疗具有重要意义。
Objectives: Determination of specificity and sensitivity of narrow band imaging (NBI) in the assessment of tumor extension in centrally located lung cancer, when compared to white light bronchoscopy (WLB) alone, and evaluation of possible influence of NBI on therapeutic decision in patients with lung cancer. Patients and methods: We evaluated 36 patients with suspected lung cancer. All patients underwent WLB followed by NBI bronchoscopy. We were using videobronchoscope BF-1T180 and EVIS LUCERA SPECTRUM processor unit. Results: Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for NBI in the assessment of tumor extension were 97.8, 85, 93.7, and 94.4%, respectively; and for WLB 92.3, 60, 69.6, and 88.9%, respectively. In 14 patients, NBI revealed more extensive tumor than WLB (p = .0057). In eight patients, NBI showed significant influence on therapeutic decision (p = .001). Conclusion: NBI videobronchoscopy had better specificity and sensitivity in the assessment of tumor extension in centrally located lung cancer, and it might play a significant role in the therapeutic decision.