Self-attraction Removal from Oritatami Systems
Self-attraction Removal from Oritatami Systems
复制标题
从 Oritatami 系统中去除自吸引
DOI：
10.1007/978-3-319-60252-3_13
复制
发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Seki Shinnosuke
中科院分区：
文献类型：
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作者：
Han Yo-Sub;Kim Hwee;Rogers Trent A.;Seki Shinnosuke
RNA共转录折叠是指RNA转录物在被RNA聚合酶从基因中合成时发生自身折叠的现象。Oritatami是这一现象的计算模型，它根据其规则集，通过珠子之间的相互作用，让其从有限的字母折叠中获得的珠子序列协同转录。在这篇文章中，我们研究了消除自吸引的问题，即在不改变其行为的情况下，让一颗珠子与另一颗相同类型的珠子从给定的oritatami系统中相互作用。自我吸引是构建内在口音系统的主要挑战之一，它甚至可以模拟所有口音系统的动态。
RNA cotranscriptional folding refers to the phenomenon in which an RNA transcript folds upon itself while being synthesized out of a gene by an RNA polymerase. Oritatami is a computational model of this phenomenon, which lets its sequence of beads (abstract molecules) taken from a finite alphabetfold cotranscriptionally via interactions between beads according to its rule set. In this paper, we study the problem of removing self-attractions, which lets a bead interact with another bead of the same kind, from a given oritatami system without changing its behavior. Self-attraction is one of the major challenges in the construction of intrinsic oritatami systems, which can simulate even the dynamics of all the oritatami systems.