The Maternal Gut Microbiome During Pregnancy.

The Maternal Gut Microbiome During Pregnancy.
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DOI:
10.1097/nmc.0000000000000372
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发表时间:
2017
期刊:
MCN. The American journal of maternal child nursing
影响因子:
--
通讯作者:
Corwin EJ
Corwin EJ
中科院分区:
其他
文献类型:
--
作者:
Edwards SM;Cunningham SA;Dunlop AL;Corwin EJ

文献摘要

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The gut microbiome is a critical component of an individual’s metabolism and overall health. The prenatal period is marked by unique inflammatory and immune changes that alter maternal gut function and bacterial composition as the pregnancy advances. The composition of the maternal gut microbiome contributes to obstetric outcomes with long-term health sequelae for mother and child. Estrogen and progesterone also impact gut function, especially during the prenatal period. These physiologic changes in pregnancy allow for adjustments in maternal metabolism and weight necessary to support the pregnancy. This article will review the normal hormonal, metabolic and immunologic changes to the maternal gut microbiome throughout the prenatal period, in addition to relevant implications for nurses providing care for pregnant women.