2‐D transmitral flows simulation by means of the immersed boundary method on unstructured grids
2‐D transmitral flows simulation by means of the immersed boundary method on unstructured grids
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DOI：
10.1002/fld.278
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发表时间：
2002-04
影响因子：
1.8
通讯作者：
F. Denaro;F. Sarghini
中科院分区：
文献类型：
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作者：
F. Denaro;F. Sarghini
计算流体动力学与临床研究之间的相互作用最近使得人们能够更深入地了解涉及心血管机制的复杂现象的生理学。本文的目的是开发一个基于浸入边界法的简化数值模型并进行数值模拟，以研究心脏舒张期，在此期间左心室充满从心房流经二尖瓣的血液。由于临床医生面临的诊断问题之一是缺乏通过生态多普勒技术获得的速度测量对舒张性能的明确定义，因此数值模拟应该提供对舒张物理学和实验数据解释的深入了解。提出了浸入边界法在非结构化网格上的创新应用，满足与沿移动浸入边界形成薄边界层相关的精度要求。当涉及广泛的空间尺度和移动边界时，非结构化网格和浸入边界方法之间的耦合似乎是一种很有前途的技术。在一系列生理参数下进行数值模拟，并与实验数据进行定性比较，以证明尽管模型经过简化，但舒张期的主要生理特征得到了很好的体现。版权所有 © 2002 约翰威利父子有限公司
Interaction between computational fluid dynamics and clinical researches recently allowed a deeper understanding of the physiology of complex phenomena involving cardio‐vascular mechanisms. The aim of this paper is to develop a simplified numerical model based on the Immersed Boundary Method and to perform numerical simulations in order to study the cardiac diastolic phase during which the left ventricle is filled with blood flowing from the atrium throughout the mitral valve. As one of the diagnostic problems to be faced by clinicians is the lack of a univocal definition of the diastolic performance from the velocity measurements obtained by Eco–Doppler techniques, numerical simulations are supposed to provide an insight both into the physics of the diastole and into the interpretation of experimental data. An innovative application of the Immersed Boundary Method on unstructured grids is presented, fulfilling accuracy requirements related to the development of a thin boundary layer along the moving immersed boundary. It appears that this coupling between unstructured meshes and the Immersed Boundary Method is a promising technique when a wide range of spatial scales is involved together with a moving boundary. Numerical simulations are performed in a range of physiological parameters and a qualitative comparison with experimental data is presented, in order to demonstrate that, despite the simplified model, the main physiological characteristics of the diastole are well represented. Copyright © 2002 John Wiley & Sons, Ltd.