Single tracking location acoustic radiation force impulse viscoelasticity estimation (STL-VE): A method for measuring tissue viscoelastic parameters.
Single tracking location acoustic radiation force impulse viscoelasticity estimation (STL-VE): A method for measuring tissue viscoelastic parameters.
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DOI：
10.1109/tuffc.2014.006775
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发表时间：
2015-07
期刊：
影响因子：
--
通讯作者：
McAleavey SA
中科院分区：
文献类型：
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作者：
Langdon JH;Elegbe E;McAleavey SA
横波弹性成像（SWEI）是一种检测组织间弹性差异的方法。与多跟踪定位（MTL）型的swi相比，它具有抑制固有散斑偏置的优点。然而，线性模型的假设导致粘弹性介质中剪切模量的高估。引入了一种新的重建技术，即单跟踪位置粘度估计（STL-VE），以纠正这种高估。该技术利用STL-SWEI成像中生成的相同原始数据。在这里，STL-VE技术是通过对一般粘弹性材料的最大似然估计（MLE）来发展的。然后将该方法用于Kelvin-Voigt模型的特殊情况。利用仿真数据对STL-VE技术进行了验证，并对该估计器的性能进行了表征。最后，采用STL-VE方法对离体牛肝脏的粘弹性参数进行估计。我们发现STL-VE结果与仿真参数吻合良好，肝脏横波数据与模型数据吻合良好。
Single Tracking Location (STL) Shear wave Elasticity Imaging (SWEI) is a method for detecting elastic differences between tissues. It has the advantage of intrinsic speckle bias suppression compared to Multiple Tracking Location (MTL) variants of SWEI. However, the assumption of a linear model leads to an overestimation of the shear modulus in viscoelastic media. A new reconstruction technique denoted Single Tracking Location Viscosity Estimation (STL-VE) is introduced to correct for this overestimation. This technique utilizes the same raw data generated in STL-SWEI imaging. Here, the STL-VE technique is developed by way of a Maximum Likelihood Estimation (MLE) for general viscoelastic materials. The method is then implemented for the particular case of the Kelvin-Voigt Model. Using simulation data, the STL-VE technique is demonstrated and the performance of the estimator is characterized. Finally, the STL-VE method is used to estimate the viscoelastic parameters of ex-vivo bovine liver. We find good agreement between the STL-VE results and the simulation parameters as well as between the liver shear wave data and the modeled data fit.