Novel antioxidant compounds from tart cherries (Prunus cerasus)
Novel antioxidant compounds from tart cherries (Prunus cerasus)
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DOI：
10.1021/np980268s
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发表时间：
1999-01-01
影响因子：
5.1
通讯作者：
Gray, JI
中科院分区：
文献类型：
--
作者：
Wang, HB;Nair, MG;Gray, JI
As indicated by an Fe(II)-induced liposome peroxidation bioassay, the EtOAc extract of tart cherries (Prunus cerasus) was found to have strong antioxidant activity. Purification of this extract afforded chlorogenic acid methyl ester (1) and three novel compounds, 2-hydroxy-3-(o-hydroxyphenyl) propanoic acid (2); 1-(3',4'-dihydroxycinnamoyl)-cyclopenta- 2,5 -diol (3), and 1-(3',4'-dihydroxycinnamoyl)-cyclopenta-2,3-diol (4), as determined by their spectral data. At a 20-mu M concentration, the antioxidant activities of compounds 3 and 4 were comparable to the antioxidant activities of caffeic acid, whereas compound 1 showed activity similar to chlorogenic acid. Also, these compounds showed antioxidant activities similar to the commercial antioxidants tert-butylhydroquinone and butylated hydroxytoluene. However, compound 2 was not active when tested at a 100-mu M concentration.
