Activation of Nrf2/NQO1 Pathway Attenuates Oxidative Stress in Neuronal Cells Induced by Microwave and Protects Neurite Development
Activation of Nrf2/NQO1 Pathway Attenuates Oxidative Stress in Neuronal Cells Induced by Microwave and Protects Neurite Development
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DOI：
10.3967/bes2021.129
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Zhang Hong
中科院分区：
文献类型：
--
作者：
Hu Shaohua;Lu Li;Wang Hui;Zhao Li;Dong Ji;Peng Ruiyun;Zhang Hong
In previous decades, people were concerned about their health because of growing environmental influences. The advancements in pulsed power technologies have increased the availability of microwave transmitters. The possible health problems caused by the widespread use of microwaves have attracted attention in recent years. This includes wireless communication technology, radar, and microwave ovens. Many studies have assessed the health risks and investigated the biological consequences of microwaves on the nervous system[1]. Studies have also demonstrated that microwave induces learning and memory deficits, possibly because the hippocampus is particularly sensitive to microwave exposure[2,3]. The swollen mitochondria could be detected in hippocampal neurons of microwave-exposed rats and neuron-like cells[2,4]. Defective mitochondria have a potential for futile adenosine triphosphate (ATP) hydrolysis and accelerated reactive oxygen species (ROS) production, resulting in neurological damage or death.
