Fatal Legionnaires' disease coincident with initiation of immunosuppressive therapy.
Fatal Legionnaires' disease coincident with initiation of immunosuppressive therapy.
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致命军团病与免疫抑制治疗的开始同时发生。
DOI：
10.1001/archinte.1985.00360060206034
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发表时间：
1985
影响因子：
--
通讯作者：
E. Renner
中科院分区：
文献类型：
--
作者：
P. Sheldon;R. Tight;E. Renner
1例既往接受过30天肠外葡庚糖酸红霉素治疗的患者在开始化疗时发生致命性军团病复发。痰液检查采用嗜肺军团菌直接荧光抗体试验表明，在抗生素治疗过程中感染持续存在。本病例提示，对于痰液直接荧光抗体检测呈阳性的患者，无论既往是否接受过抗生素治疗，均应延迟免疫抑制剂的给药。
A fatal relapse of legionnaires' disease occurred coincidental with the initiation of chemotherapy in a patient who had received previous parenteral erythromycin gluceptate therapy for 30 days. Sputum examinations utilizing the direct fluorescent antibody test for Legionella pneumophila suggested persistence of infection during the course of antibiotic therapy. This case suggests that administration of immunosuppressive agents should be delayed in patients whose sputum is positive on direct fluorescent antibody testing, regardless of previous antibiotic therapy.