Spatial simulation of actin filament dynamics on structured surfaces
Spatial simulation of actin filament dynamics on structured surfaces
复制标题
结构化表面上肌动蛋白丝动力学的空间模拟
DOI:
--
复制
发表时间:
2012
期刊:
影响因子:
--
通讯作者:
J. Nebe
中科院分区:
文献类型:
--
作者:
Arne T. Bittig;A. Uhrmacher;C. Matschegewski;J. Nebe
We develop a simple model of actin filament growth in bone cells comprising integrin receptors, actin molecules able to form chains and cofilin molecules destroying chains. The model is expressed in the ML-Space modeling language and simulated using a particle-based approach. We find the model to be a promising starting point in reproducing in silico experimentally observed filament growth behavior of bone cells on different surface structures.
影响因子:
3.4
作者:
Matschegewski, Claudia;Staehlke, Susanne;Nebe, J. Barbara
通讯作者:
Nebe, J. Barbara