Skin‐Adhesive, ‐Breathable, and ‐Compatible Nanopaper Electronics for Harmonious On‐Skin Electrophysiological Monitoring
Skin‐Adhesive, ‐Breathable, and ‐Compatible Nanopaper Electronics for Harmonious On‐Skin Electrophysiological Monitoring
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DOI：
10.1002/admi.202202263
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发表时间：
2023-04
影响因子：
5.4
通讯作者：
Yintong Huang;T. Araki;Naoko Kurihira;T. Kasuga;T. Sekitani;M. Nogi;Hirotaka Koga
中科院分区：
文献类型：
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作者：
Yintong Huang;T. Araki;Naoko Kurihira;T. Kasuga;T. Sekitani;M. Nogi;Hirotaka Koga
皮肤上的电子学提供了从皮肤提取电生理信号的接口，人们利用安装在柔性衬底上的电极对其进行了深入的研究。尽管在基板设计方面做出了许多努力以优化使用者的舒适性，但具有皮肤粘附性、皮肤透气性、皮肤兼容性、机械耐用性、灭菌性、可持续性和生物降解性的基板仍然是人类和环境友好型皮肤上电子产品的理想候选者。为此，本研究开发了一种具有定制多孔纳米结构的木质纤维素纳米纤维纸(简称纳米纸)。定制的多孔纳米纸能够通过水辅助变形来实现皮肤顺应性，从而实现卓越的皮肤粘附力，以及高皮肤透气性和兼容性，优于传统的皮肤上电子设备基板。通过在多孔纳米纸上安装金电极并将其附着在人体皮肤上，成功地实现了对脑电、肌电和心电图的实时监测，以诊断人体的生理状态。此外，安装在金电极上的多孔纳米纸具有独特的特性，包括抗皮肤变形的耐用性、可重复使用，甚至由于其高机械耐久性和热稳定性而可灭菌。因此，所制备的多孔纳米纸为人体和环境和谐的皮肤电子设备提供了一个迷人的平台。
On‐skin electronics, which offers an interface for extracting electrophysiological signals from skin, is intensively investigated using electrodes mounted on flexible substrates. Despite numerous efforts toward substrate design to optimize user comfort, substrates with skin‐adhesion, skin‐breathability, skin‐compatibility, mechanical endurance, sterilizability, sustainability, and biodegradability remain desirable candidates for human‐ and environment‐friendly on‐skin electronics. To this end, a wood‐derived cellulose nanofiber paper (denoted nanopaper) with customized porous nanostructures is developed in this study. The customized porous nanopaper enables water‐assisted deformation for skin‐conformability, thereby realizing outstanding skin‐adhesion force, along with high skin‐breathability and compatibility, superior to those of conventional substrates reported for on‐skin electronics. By mounting gold electrodes on the porous nanopaper and adhering them to human skin, the real‐time monitoring of electroencephalogram, electromyogram, and electrocardiogram for diagnosing the human physiological state is successfully achieved. Furthermore, the gold‐electrode‐mounted porous nanopaper affords unique characteristics including durability against skin deformation, reusability, and even sterilizability, owing to its high mechanical endurance, and thermal stabilities. Thus, the as‐prepared porous nanopaper serves a fascinating platform for human‐ and environment‐harmonious on‐skin electronics.