Megakaryocyte fragments and the microtubule coil.
Megakaryocyte fragments and the microtubule coil.
复制标题
巨核细胞碎片和微管线圈。
DOI：
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发表时间：
1987
期刊：
影响因子：
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通讯作者：
Hartshorn Ma
中科院分区：
文献类型：
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作者：
Radley Jm;Hartshorn Ma
我们已经检查了巨核细胞过程碎片，这些碎片在短时间孵育后从骨髓外植体中迁移出来，并呈现珠状，由2个或更多假定的血小板组成。碎片似乎发生在体内，并支持的建议，血小板解放并不总是发生在一个连续的方式从巨核细胞过程的远端。透射电子显微镜显示，微管一般是纵向取向的过程片段。很少，微管线圈被发现在一个终端位于假定的血小板。这些观察结果支持这样的观点，即微管的边缘卷曲是循环血小板的特征，通常在血小板被释放后才形成。
: We have examined megakaryocyte process fragments that migrate out of bone marrow explants after a short period of incubation and assume a beaded form, consisting of 2 or more putative platelets. The fragmentation appears to occur in vivo and supports the proposal that platelet liberation does not always occur in a sequential manner from the distal ends of megakaryocyte processes. Transmission electron microscopy revealed that microtubules were generally oriented longitudinally in the process fragments. Rarely, a microtubule coil was found in a terminally located putative platelet. The observations favour the view that the marginal coil of microtubules, which is a characteristic of circulating platelets, does not usually form until after platelets have been liberated.